ABSTRACT
We report the success of oral cyclosporine therapy in a patient with severe vision-threatening vernal keratoconjunctivitis. A child presented with severe allergy which was not controlled with topical steroids, cyclosporine and mast cell stabilizers. Oral steroids were required repeatedly to suppress inflammation. Child showed a dramatic improvement and stabilization with oral cyclosporine therapy. Oral cyclosporine therapy can be tried in severe vision-threatening allergy refractory to conventional therapy.
Subject(s)
Administration, Oral , Child , Conjunctiva/pathology , Conjunctivitis, Allergic/diagnosis , Conjunctivitis, Allergic/drug therapy , Cornea/pathology , Cyclosporine/administration & dosage , Dose-Response Relationship, Drug , Drug Resistance/drug effects , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Immunosuppressive Agents/administration & dosage , Male , Retrospective Studies , Severity of Illness IndexABSTRACT
We report a case of surgically induced necrotizing scleritis following pterygium surgery with the bare sclera technique, without the use of adjunctive irradiation or mitomycin C. The patient was successfully treated with systemic immunosuppression.
Subject(s)
Female , Follow-Up Studies , Humans , Immunosuppressive Agents/therapeutic use , Middle Aged , Ophthalmologic Surgical Procedures/adverse effects , Postoperative Complications , Pterygium/surgery , Scleritis/drug therapyABSTRACT
We report a case of nocardiosis in a 42, years male with common variable immunodeficiency syndrome (CVID). He presented with arthritis, subcutaneous abscess and pleural effusion. Diagnosis of CVID was made during this presentation. Serum IgG, IgA and IgM levels were markedly decreased. Nocardia asteroides was cultured from pleural fluid. He was successfully treated with intravenous immunoglobulin and cotrimoxazole.